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Editor’s note: This story has been updated with information from the Tennessee Bureau of Investigation on the initial whereabouts of Amber Clare.

SAN CLEMENTE, Calif. — Authorities are asking San Diegans to keep an eye out for two missing children and the family member suspected of kidnapping one of them earlier this month. The suspect’s car was found Tuesday in San Clemente.

The case of 3-year-old Noah Clare and 16-year-old Amber Clare has developed into a multi-state manhunt over the past several weeks involving a web of local agencies.

Noah was taken from Gallatin, Tennessee on Nov. 6, according to the Tennessee Bureau of Investigation. Amber, meanwhile, has been missing from Beaver Dam, Kentucky since the same date, WKRN reports.

Jacob Clare, Noah’s father and Amber’s uncle, is believed to be traveling with both children.

The 35-year-old Kentucky resident is suspected of “especially aggravated kidnapping” in Noah’s disappearance, officials in Tennessee say. While the teenage Amber was initially considered a “runaway” by authorities in Kentucky, she has been included in recent alerts about the case as an “endangered missing” person.

Jacob’s vehicle, a Subaru Legacy, was located in southern Orange County Tuesday, but investigators say neither he nor the children have been found. “They were last seen in San Clemente and might be heading to San Diego,” the San Diego County Sheriff’s Department wrote on Twitter Wednesday morning.

A photo shared by authorities shows the abandoned car was loaded with supplies, including camping equipment and MREs — ration-style meals used in military or disaster settings.

Noah is 3 feet, 5 inches tall, weighs 40 pounds, and has brown hair and blue eyes, according to California Highway Patrol. Amber is described as 5 feet, 7 inches tall, weighing 135 pounds with brown hair and green eyes.

Jacob is 6 feet, 7 inches tall, weighs 200 pounds and has brown hair and green eyes, investigators said. He is “believed to be armed and dangerous,” CHP added.

The agency has issued an advisory for both children that covers Orange, Los Angeles, San Bernardino, San Diego and Ventura counties. Officials in Tennessee have issued an Amber Alert for Noah specifically.

Amber’s family has been begging authorities to formally issue an Amber Alert for her as well, according to WKRN. That decision would be up to Kentucky State Police, the TBI said on Twitter, because she was never believed to be in Tennessee.

The teen’s mother told local media that Amber has a medical condition that requires her to take seizure medication. Her prescription was left at home and Amber’s loved ones worry her condition will worsen without it.

Anyone with information about the case or who believes they have seen Clare or the children is urged to call 911.

The KTLA Digital Team contributed to this report.