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SAN DIEGO — The Port of San Diego Board of Commissioners next week will consider a staff recommendation to open negotiations with The Brigantine Inc. to lease and renovate the iconic Anthony’s restaurant site on the downtown waterfront.

Port staff say an initial proposal submitted by the Brigantine, which operates six seafood restaurants in San Diego County, scored the highest of six respondents. A staff report said a supplemental proposal and financial terms offered by the Brigantine make it the best option.

In August, the board directed staff to consider the Brigantine proposal along with those from Sunroad Enterprises and the current lessee, Anthony’s Fish Grotto.

“The San Diego destination deserves a world-class restaurant anchor at this prominent site — one that showcases the unique location, attracts people to the waterfront and promotes the culture and beauty of our region,” said Port CEO Randa Coniglio. “The port team used a rigorous procurement process to compare the advantages of several excellent redevelopment proposals for this restaurant site.”

According to a staff report, Brigantine proposes to operate four eateries in the 16,600-square-foot space at 1360 N. Harbor Drive — a Brigantine seafood restaurant, and a Miguel’s Cocina, a Mexican food chain also owned by Brigantine.

The other two would be Ketch Grill & Taps, a casual walk-up, dine-in and take-out grill that offers local craft beers and spirits, and Portside Gelato & Coffee, which would include coffee and espresso from San Diego roaster Cafe Moto.

The proposal also includes a public viewing deck and an expanded dock- and-dine facility.

The company has proposed investing at least $13 million into the project and paying a minimum annual rent of $1.1 million, which staff rated the best financial deal of the three finalists, or $1.6 million higher than the others over a 10-year period.

After the commissioners choose a prospective lessee, staff will open negotiations and begin the environmental review process. An eventual lease contract and EIR would require final board approval.

Anthony’s has leased the space since 1965, but the deal is set to expire Jan. 31, 2017, according to the staff report.

The commissioners will have the options at Tuesday’s meeting to accept, modify or deny the staff recommendation.