The incident happened around 8:40 p.m. in the 3200 block of Mission Avenue, near Airport Road.
Police said the woman was in a crosswalk attempting to cross the westbound lanes of Mission Avenue against a red light while the tow truck driver, who had a green light, was headed westbound. The truck hit the woman in the intersection. The woman was pronounced dead at the scene.
The truck driver was interviewed by officers before being released from the scene.
Westbound Mission Avenue from Roymar Road to Airport Road will be closed for several hours while officers investigate, police said.