Ruben Loya will climb the mountain 43 times over six days to represent the number of children who are diagnosed with cancer every day and the average age children are diagnosed.
After his daughter was diagnosed with liver cancer, Loya made pediatric cancer awareness his mission.
"When you first hear about it, it's like a train hitting you. You don't know what to do. You don't know what to think. It's an emotional roller coaster," Loya said. "You have your faith and you have your family and you try to get through it one day at a time."
Once Loya's daughter went into remission, he says he wanted to do more.
"I can do more by dressing up as a superhero and making superhero appearances at hospitals," Loya said.
When finished, Spider-Man will have climbed almost 140 miles.
If you'd like to help Loya's cause, click here for more information.