Cesar Castillo of Chula Vista turned himself in to authorities at San Ysidro Port of Entry about 2:15 p.m., according to police.
Castillo is accused of repeatedly running over his 37-year-old wife, Leonor, with his 1998 Chevrolet Silverado in the 1100 block of Elm Avenue in Chula Vista shortly before 7 p.m. Friday. She died at the scene.
“The act is believed to have been intentional,'' CVPD Capt. Roxana Kennedy said.
Investigators believed the suspect, also 37, fled to Mexico following his wife's death.