The crash at Slaughterhouse Canyon Road was reported at 5:33 a.m., according to the California Highway Patrol, which diverted traffic onto San Vicente Road until around 6:45 a.m.
Paramedics took one person to Sharp Memorial Hospital, a Heartland dispatcher said. The extent of the injury and the identity of the injured person were not immediately released.
Earlier reports that a marked San Diego police vehicle was involved were incorrect, according to SDPD Det. Gary Hassen, who said a San Diego police officer pulled up on the scene shortly after the crash and reported it.