The armed robbery at the 7-Eleven at 3603 College Ave. occurred at around 2:45 a.m., according to San Diego police Sgt. David Jennings.
The exact loss was not immediately determined, the sergeant said in a statement.
Police described one gunman as black, around 5 feet 10 and 190 pounds. The other was black, roughly 5 feet 7 and 200 pounds, Jennings said, noting that both robbers wore bandanas over their faces.